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Samsca
Generic Samsca ( Tolvaptan )
Samsca (Tolvaptan) is an oral medication used to treat low blood sodium levels (hyponatremia) associated with conditions such as heart failure or SIADH (syndrome of inappropriate antidiuretic hormone). It works by blocking the effects of vasopressin, a hormone that causes the body to retain water, thus helping to restore the natural balance of fluids. Samsca promotes the excretion of free water without significant loss of sodium or potassium, making it distinct from traditional diuretics.
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15 mg
10 piller
Samsca
zl286.65
zl 238.87
zl 23.89 per pille
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+ Neste bestillinger 10% rabatt
15 mg
20 piller
Samsca
zl564.52
zl 470.42
zl 23.52 per pille
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15 mg
30 piller
Samsca
zl833.56
zl 694.63
zl 23.16 per pille
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15 mg
60 piller
Samsca
zl1640.70
zl 1367.24
zl 22.79 per pille
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15 mg
90 piller
Samsca
zl2421.37
zl 2017.80
zl 22.42 per pille
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spare: zl 132.32
15 mg
120 piller
Samsca
zl3175.58
zl 2646.31
zl 22.05 per pille
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spare: zl 220.53
15 mg
180 piller
Samsca
zl4683.99
zl 3903.32
zl 21.69 per pille
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spare: zl 396.95
30 mg
10 piller
Samsca
zl366.04
zl 305.03
zl 30.51 per pille
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30 mg
20 piller
Samsca
zl727.71
zl 606.42
zl 30.32 per pille
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30 mg
30 piller
Samsca
zl1080.55
zl 900.46
zl 30.03 per pille
+ Gratis standard luftpost tjeneste
+ Pakke levering forsikring
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30 mg
60 piller
Samsca
zl2143.50
zl 1786.25
zl 29.77 per pille
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+ Pakke levering forsikring
+ Neste bestillinger 10% rabatt
30 mg
90 piller
Samsca
zl3157.94
zl 2631.61
zl 29.26 per pille
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spare: zl 112.47
30 mg
120 piller
Samsca
zl4137.08
zl 3447.56
zl 28.74 per pille
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spare: zl 211.71

Common Use
Samsca is primarily used to correct clinically significant hyponatremia (low sodium levels) in patients with normal blood volume or fluid overload, particularly when associated with heart failure or SIADH.

Dosage and Direction
Samsca is usually prescribed starting at 15 mg once daily, with adjustments made based on the patient’s response and sodium levels. It should be taken orally, with or without food, and under hospital supervision during initiation to monitor sodium correction.

Precautions
Frequent monitoring of serum sodium is essential to avoid overly rapid correction. Samsca should not be used for more than 30 days in patients with autosomal dominant polycystic kidney disease due to potential liver injury. Avoid dehydration and ensure adequate fluid intake. Not recommended for patients unable to sense or respond to thirst.

Contraindications
Do not use Samsca in patients with urgent need to raise sodium levels, those unable to drink, with anuria, or with significant liver impairment. It is also contraindicated with strong CYP3A inhibitors like ketoconazole or clarithromycin.

Possible Side Effects
Common side effects include thirst, dry mouth, frequent urination, constipation, and weakness. More serious effects may include rapid sodium correction (leading to neurologic symptoms), liver injury, or dehydration.

Drug Interaction
Tolvaptan may interact with CYP3A inhibitors or inducers, increasing or decreasing drug levels. Use caution with digoxin and diuretics, as additive effects on electrolytes and fluid balance may occur.

Missed Dose
If a dose is missed, take it as soon as remembered. If it’s close to the time for the next dose, skip the missed dose. Do not double up to make up for a missed one.

Overdose
Symptoms of overdose may include excessive urination, dehydration, and electrolyte imbalance. Seek immediate medical attention if overdose is suspected.

Storage
Store Samsca at room temperature (68–77°F or 20–25°C), away from moisture and heat. Keep the medication in its original packaging and out of reach of children.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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